West Chester University Covid 19 & Cancer Study Questions
Description
Assignment I: Covid 19 Study.
Review article: Arshad, S., Kilgore, P., Chaudhry, Z. S., Jacobsen, G., Wang, D. D., Huitsing, K.,
& ONeill, W. (2020). Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19. International Journal of Infectious Diseases. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC73305
Question: Do you agree with the authors conclusions? Why/why not? What additional information would you need to know as an epidemiologic critic before you believed the conclusions. Identify any issues with the study that make their findings invalid. Use information on Table 1 for your assessment
Assignment II Study designs
Question 1: For each of the following scenarios, indicate what kind of study (case control, retrospective or prospective, randomized trial or cross-sectional) is being described here and how you determined the study design.
Four hundred patients with newly diagnosed myocardial infarction were matched with a sample of population controls by age and sex. History of smoking was then asked and compared in the two groups. What is the study design? On what basis did you determine the study design?
Fifty thousand healthy men were asked whether they have had a vasectomy. All the men were then followed for 4 years to compare the development of prostate cancer in vasectomized versus non-vasectomized men. What study design? On what basis did you determine the study design?
To determine the relationship between malaria and nutrition, children in a village were simultaneously assessed for malaria antibodies and nutritional status. What study design? On what basis did you determine the study design?
One hundred women were given aspirin to take everyday for one year and another hundred were given placebo tablets to take each day. Both groups were followed and the rate of development of stroke was compared in the two groups. What study design? On what basis did you determine the study design?
Question 2: You are an epidemiologist working for the national Cancer Institute. You are asked to design a cohort study to examine the relationship between dietary intake of soy protein and the risk of breast cancer.
Design a study to answer this question: what is the association between dietary intake of soy protein and the risk of breast cancer?
What group of women would you choose as your exposed group? Where will you find them?
What group(s) of women would you choose as your unexposed? Where would you find them?
How would you collect information on exposure (dietary intake of soy)? Identify your sources of information
How would you collect information on outcome (breast cancer)? Identify sources of information
Would you use a prospective or retrospective cohort design? Justify your choice
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